Wednesday, 20 June 2012

CareCrunch Answers ? Answers Archive ? Superb Advice On ...

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Violence spikes across southern Afghanistan

KABUL, Afghanistan (AP) ? Violence spiked in southern Afghanistan as militants stormed a NATO military base and attacked a police checkpoint Tuesday, a day after gunmen wearing police uniforms killed a U.S. soldier.

The heaviest fighting in Afghanistan this summer has been in the south and east where Afghan forces are increasingly taking charge of security from their international partners. That could signal a rocky transition as foreign combat troops are due to withdraw by the end of 2014.

Most of the attacks over the past two days occurred in the southern Kandahar province, the Taliban's birthplace.

Insurgents attacked a NATO base before dawn Tuesday in Kandahar's Shah Wali Kot district, but no service members were killed, the U.S.-led coalition said.

"Initial reports indicate that seven insurgents launched an attack on a NATO installation and initially were successful in breaching the outer security perimeter," NATO said in a statement. "Current reporting indicates all the attackers have been killed."

The Taliban claimed responsibility for the attack, saying it was targeting troop sleeping quarters.

Provincial government spokesman Javid Faisal said initial reporting indicated that at least one foreign worker was killed and two other foreigners were wounded, but the report could not be independently confirmed.

A few hours later, militants wearing Afghan police uniforms attacked a police checkpoint in Kandahar city. Three policemen were killed and nine others were wounded during an hour-long gun battle that ensued, according to the Ministry of Interior. Four militants also died.

The Taliban again claimed responsibility and said the clash lasted six hours.

The U.S. and other foreign troops have increasingly been targeted by Afghan security forces, or militants disguised in their uniforms.

On Monday, three gunmen dressed in Afghan police uniforms killed one American service member and wounded nine others in Kandahar's Zhari district, U.S. officials said, speaking on condition of anonymity because the attack was still under investigation. Faisal, the spokesman for Kandahar province, said the attackers fired a rocket-propelled grenade at the coalition forces and then fled the scene.

The Defense Department said U.S. Army Pfc. Jarrod Lallier, 20, of Spokane, Washington, died after his unit was attacked with small arms fire and grenades. He was assigned to the 1st Battalion, 508th Parachute Infantry Regiment, 4th Brigade Combat Team, 82nd Airborne Division from Fort Bragg, North Carolina.

Efforts to draw down the number of U.S. troops in Afghanistan rely on the Americans working closely with their Afghan partners to train and mentor them so that they can take over the security of their country. Such insider attacks fuel distrust between the two forces and have triggered increased security protections for the U.S. service members serving in Afghanistan.

It remains unclear whether the gunmen were actual members of the Afghan National Police or militants dressed in their uniforms.

The number of insider attacks in the country has escalated, with more than a dozen fatal assaults already this year that have led to more than 20 deaths.

Last year 21 fatal attacks killed 35 coalition service members, according to the coalition. That compares with 11 fatal attacks and 20 deaths the previous year. In 2007 and 2008 there were a combined total of four attacks and four deaths.

The increase accelerated after a series of mistakes and other behavioral problems by U.S. troops serving in Afghanistan, including the burning of Qurans and other religious materials earlier this year at a U.S. base north of Kabul.

Separately, the coalition said a NATO service member was killed Tuesday in an insurgent attack in southern Afghanistan. No other information was released so it was unclear whether the service member died in one of the attacks in Kandahar province or elsewhere in the south. So far this year, 200 NATO service members have been killed in Afghanistan.

In other violence Tuesday, gunmen assassinated two local government employees in the Chaparhar district of Nangarhar province in eastern Afghanistan, said the governor's spokesman, Ahmad Zia Abdulzai. The Taliban routinely target Afghan officials in an attempt to weaken the resolve of a government they say is collaborating with foreign occupiers.

Civilians also continued to be targeted.

A car hit a roadside bomb Monday in the Musa Qala district of southern Helmand province, killing eight civilians, including women and children, the governor's office said in a statement issued on Tuesday.

Meanwhile, Afghan authorities announced that two men have been charged in connection with a Dec. 6 suicide bombing that killed 56 worshippers and wounded more than 160 others last year outside a Shiite shrine in Kabul. It was Afghanistan's first major sectarian assault since the fall of the Taliban regime more than a decade ago.

Officials with the Afghan intelligence service and Attorney General Mohammed Ishaq Aloko told reporters the two men confessed to transporting the suicide attacker from Peshawar, a city in northwest Pakistan, to the shrine in Kabul.

Lashkar-e-Jhangvi, a Pakistan-based group that has carried out other attacks against Shiite Muslims, claimed responsibility for the bombing.

The attorney general said the bombing was an attempt to create division between Afghan Sunni and Shiite Muslims. He alleged that the Pakistani intelligence service was involved in the attack during the period of Ashoura, which marks the seventh century death of Imam Hussein, a grandson of the Prophet Muhammad.

Pakistan has repeatedly denied Afghan officials' allegations that it facilitates attacks in Afghanistan.

One of the men, Rahim Gul from Bati Kot district of Nangarhar province, told officials on a taped confession that he transported the suicide bomber because he was poor and badly needed the 10,000 Pakistani rupees (about $106) the organizers of the plot had agreed to pay him. The second man charged, Habibullah, who uses only one name, is from Nangarhar's Surkh Rod district.

___

Associated Press writers Mirwais Khan in Kandahar and Rahim Faiez and Amir Shah in Kabul contributed to this report.

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APNewsBreak: Likely insider attack kills US troop

WASHINGTON (AP) ? U.S. officials say that an American service member was killed and several others were injured when individuals dressed in Afghan police uniforms turned their guns on them in southern Afghanistan Monday.

The shootings are the latest in a growing number of possible insider attacks against U.S. forces.

Jamie Graybeal, a spokesman for the International Security Assistance Force in Afghanistan, confirmed the death, and said that the three Afghan shooters fled and are being sought. Although they were wearing police uniforms, it was not yet clear if they were actually Afghan forces or just had the clothing.

Other U.S. officials said that as many as eight U.S. troops were injured, mostly with fairly minor wounds. The officials spoke on condition of anonymity to discuss an investigation.

Associated Press

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Tuesday, 19 June 2012

Klout: We?ve Delivered 700K Perks Across 350 Campaigns

klout logoDo Klout Perks ? where brands can offer special goods and services to users with the right Klout scores ? work? Well, Klout is releasing some numbers suggesting that the program has considerable momentum. The company says it has been about two years since it launched the Klout Perks program in July 2010. Since then, it has delivered 700,000 perks in more than 350 campaigns. More than 300 brands have participated, including Disney, Microsoft, HBO, American Express, Chili?s, Chevy, Spotify, and Gilt And customers seem happy with their Perks, giving them an average customer satisfaction rating of 4 out of 5 stars.

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Huguette Clark's Huge Gifts Spotlighted In NY Court

NEW YORK ? Her nurse was showered with almost $28 million in gifts, including three Manhattan apartments, two homes elsewhere and a $1.2 million Stradivarius violin. Her doctors' families received more than $3 million in presents. A night nurse received a salary plus money to cover her children's school tuition and to help buy two apartments.

Now the court-appointed official overseeing copper heiress Huguette Clark's estate wants all these gifts ? and more ? back.

Saying the recipients manipulated the reclusive multimillionaire into lavishing largesse upon them during her long life, public administrator Ethel J. Griffin is trying to reclaim a whopping $37 million for the $400 million estate.

Besides seeking an order for return of those gifts, the administrator asked a court last month to investigate whether a hospital where Clark lived should have to give back a $6 million painting by French pre-Impressionist Edouard Manet and whether the prominent Corcoran Gallery of Art in Washington should have to return $250,000.

While clashes over who got what and how during someone's lifetime crop up in many will fights, the staggering size, two-decade timeframe and uncommon circumstances distinguish the dispute surrounding Clark's gifts.

A court will likely have to reconstruct the intentions and mental state of an eccentric woman who died at 104 last year, and discern whether manipulation or gratitude was behind the gift-giving. Another issue is how well Clark was advised by her lawyer and her accountant. Both have come under scrutiny for their management of her affairs.

"It's like piecing together a puzzle or a mystery," says Laura Stegossi, a Philadelphia estates lawyer who isn't connected to the Clark case.

The public administrator's court papers portray a frail, secluded Clark exploited by a scheming retinue. But recipients say Clark was a generous, independent-minded woman who did exactly what she wanted in enriching people around her.

A separate fight is roiling over what will ultimately become of Clark's fortune. The last will she apparently signed, in April 2005, leaves most of her money to charity, with a more than $30 million bequest to her private nurse. Another will, signed six weeks earlier, left her estate mostly to about 20 great-nieces and great-nephews. They are challenging the latest will.

A daughter of a Montana senator who amassed his Gilded Age wealth mining copper, building railroads and founding Las Vegas, the childless, briefly married Clark owned the largest residence on Fifth Avenue and mansions in California and Connecticut. But the last 20 years of her life, she voluntarily spent in two Manhattan hospitals.

She was hospitalized in 1991 after a friend sent a doctor to see her. The physician found a 75-pound octogenarian in a disheveled apartment illuminated by a single candle, her face ravaged by skin cancer, a recent court filing says .

Clark was in better health by 1996, talking with her staff and involved in handling her affairs but still "shy and reticent, avoiding most people," though she exchanged letters with friends and relatives, Dr. Henry Singman wrote. She was unwilling to go home, even when he urged her to.

Clark paid the hospital $300,000 to $400,000 a year to care for her and hired private nurses and doctors, according to court documents. In addition, she rewarded members of her inner circle beyond their salaries.

In the quarter-century before her hospitalization, she averaged less than $40,000 a year in taxable gifts. That amount shot up afterward, the public administrator said in a May 22 court filing.

Private nurse Hadassah Peri made a salary that reached $131,000 a year, and she got roughly $28 million in real estate, jewelry, checks and other gifts, the public administrator said. Peri's family also received another $3 million. A handful of other nurses and doctors got more than $4 million among them, and Clark even paid Singman's malpractice insurance for a few years, according to the public administrator.

Accountant Irving Kamsler got $435,000 in gifts; lawyer Wallace Bock got $60,000 plus the emotional payoff of shepherding a more than $1.8 million contribution from Clark for a security system for the Israeli settlement where his daughter lives.

A judge suspended Bock and Kamsler from overseeing Clark's estate in December, after the public administrator said the two had underpaid her gift taxes by tens of millions of dollars; Kamsler resigned days before being ousted.

Separate from this dispute, the Manhattan district attorney's office has been looking into how Clark's finances were managed, people familiar with the probe told The Associated Press. They spoke on condition of anonymity because they were not authorized to discuss the matter publicly.

Neither Bock nor Kamsler has been charged with a crime, and both have denied any wrongdoing.

The public administrator says recipients induced Clark to bestow gifts when she didn't understand or wasn't properly informed about the finances and suffered from "various physical and mental infirmities." Her condition by 2009 included hallucinations and serious vision and hearing problems, Deputy Public Administrator Joy A. Thompson wrote in last month's filing, first reported by msnbc.com.

"It does not appear that anyone in a position of power or authority ever intervened to ensure that Mrs. Clark possessed the requisite capacity to make gifts and was acting of her own free will," Thompson wrote.

But recipients say Clark did act freely, and knowingly. Clark herself wrote many of the disputed checks; Bock wrote others, with Clark signing documents authorizing them.

As early as 1993, Kamsler told a previous Clark lawyer that her expenses were outstripping her income, and he and Bock at least sometimes warned her about the tax ramifications of her gifts, court documents show.

"The record will show that Wally Bock acted in Huguette Clark's interest at all times, and that he continues to desire to carry out her wishes," his lawyer, John D. Dadakis, said by phone.

Clark also gave other substantial gifts the public administrator isn't trying to reclaim, including a $10 million gift to a friend in 2000. The administrator has said some gifts were valid.

"This was a very generous woman" who made gifts to people she rarely or never saw, said Peri's lawyer, Harvey E. Corn. "It's absurd to think that she would not give gifts to the individuals who worked with her."

Lawyers for other recipients named in the public administrator's filing either declined to comment or didn't immediately return calls.

___

Follow Jennifer Peltz at http://twitter.com/jennpeltz

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New York "Soccer Mom Madam" rejects bail offer

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Sunday, 17 June 2012

Breast milk kills HIV and blocks its oral transmission in humanized mouse

Friday, June 15, 2012

More than 15 percent of new HIV infections occur in children. Without treatment, only 65 percent of HIV-infected children will live until their first birthday, and fewer than half will make it to the age of two. Although breastfeeding is attributed to a significant number of these infections, most breastfed infants are not infected with HIV, despite prolonged and repeated exposure.

HIV researchers have been left with a conundrum: does breast milk transmit the virus or protect against it?

New research from the University of North Carolina School of Medicine explores this paradox in a humanized mouse model, demonstrating that breast milk has a strong virus killing effect and protects against oral transmission of HIV.

"This study provides significant insight into the amazing ability of breast milk to destroy HIV and prevent its transmission," said J. Victor Garcia, PhD, senior author on the study and professor of medicine in the UNC Center for Infectious Diseases and the UNC Center for AIDS Research. "It also provides new leads for the isolation of natural products that could be used to combat the virus."

Garcia and colleagues pioneered the humanized "BLT" mouse model, which is created by introducing human bone marrow, liver and thymus tissues into animals without an immune system of their own. Humanized BLT mice have a fully functioning human immune system and can be infected with HIV in the same manner as humans.

In the study, the researchers first determined that the oral cavity and upper digestive tract of BLT mice have the same cells that affect oral transmission of HIV in humans and then successfully transmitted the virus to the mice through these pathways. When the mice were given virus in whole breast milk from HIV-negative women, however, the virus could not be transmitted.

"These results are highly significant because they show that breast milk can completely block oral transmission of both forms of HIV that are found in the breast milk of HIV-infected mothers: virus particles and virus-infected cells," said Angela Wahl, PhD, a post-doctoral researcher in Garcia's lab and lead author on the paper. "This refutes the 'Trojan horse' hypothesis which says that HIV in cells is more stubborn against the body's own innate defenses than HIV in virus particles."

Finally, the researchers studied the effectiveness of pre-exposure prophylaxis (PrEP) with antiretroviral medication for oral transmission of HIV. Garcia and his team have previously shown that PrEP is effective against intravenous, vaginal and rectal transmission of HIV in humanized BLT mice. In this study, they gave the mice antiretroviral drugs for seven days (3 days before and 4 days after exposing them to the virus) and found 100 percent protection against virus transmission.

These latest findings provide important leads to alternative treatments that could be used to prevent transmission.

"No child should ever be infected with HIV because it is breastfed. Breastfeeding provides critical nutrition and protection from other infections, especially where clean water for infant formula is scarce," Garcia said. "Understanding how HIV is transmitted to infants and children despite the protective effects of milk will help us close this important door to the spread of AIDS."

The study appears in the June 14, 2012 issue of the online journal PLoS Pathogens.

###

University of North Carolina Health Care: http://www.med.unc.edu

Thanks to University of North Carolina Health Care for this article.

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